Meet Dr. Chelsea Matisz

Chelsea Matisz is an award-winning gut-brain scientist & public speaker.

Our ancestors evolved in environments that shaped every cell, hormone, and reflex we have. But the world we live in now—saturated with stress, technology, and processed food—bears little resemblance to the one that built us.

This is the Ancestral Paradox: the clash between ancient biology and modern life.

Building on the evolutionary mismatch hypothesis, my work weaves together gut–brain science, stress physiology, diet, mood, and decision-making into one integrated framework for understanding resilience in the modern world.

I explore how chronic stress and nutrient-depleted diets disrupt the delicate feedback loops between the gut, immune system, and brain—draining energy, impairing focus, and reshaping the way we think and choose.

By combining scientific rigor with accessible storytelling, I help people see their biology not as broken, but as brilliantly adaptive—simply misaligned with the environment we’ve created.

When we understand this paradox, we can begin to restore balance in the gut, the brain, and the self.

Let me help you and your team understand.